A few minutes of light exercise, rather than a sweaty gym workout, is all that is needed to reduce the risk of type 2 diabetes, study suggests

Even small amounts of physical activity can offer health benefits that protect against diabetesEven small amounts of physical activity can offer health benefits that protect against diabetes, new research suggests.

A new study found that even a little exercise wards off insulin resistance, a precursor to type 2 diabetes which can result from a high-fat diet.

Insulin resistance occurs when the cells of the body stop responding to insulin, a hormone that regulates blood sugar levels in the body.

Exercise can prevent insulin resistance by prompting the body to remove damaged cells and enhancing the quality of mitochondria, the cell’s energy powerhouses.

Type 2 diabetes affects 4.5 million people living in the UK and 29 million people in the US.

Even small amounts of physical activity can offer health benefits that protect against diabetes

The study also casts doubt on the previously held view that increasing the quantity of mitochondria could help fix some consequences of a high fat diet, including insulin resistance.

The researchers found that the benefits from physical activity were not affected by the quantity of mitochondria.

Lead researcher Megan Rosa-Caldwell, a doctoral student at the University of Arkansas, found that mice genetically engineered to have higher quantity of mitochondria were not more protected against high-fat diet induced insulin resistance.

How was the research conducted?

The researchers fed all the mice in the study a Western diet high in fat.

The genetically engineered and control mice were further divided into a group that was allowed to exercise, and a sedentary group.

Their results showed that physical activity, regardless of the amount of mitochondria, offered similar health benefits against insulin resistance.

Even a little exercise wards off insulin resistance, a precursor to type 2 diabetes which can result from a high-fat diet

Study found even a little exercise wards off insulin resistance, a precursor to type 2 diabetes

The researchers said that it appears that exercise’s ability to help remove damaged cells and enhance the quality of the mitochondria may be more effective for preventing insulin resistance.

But they said these aspects need to be further tested.

Exercise offers ‘the greatest protection’

Ms Rosa-Caldwell said that with rates of obesity and type 2 diabetes continuing to increase, understanding the cellular processes that help or hurt insulin resistance can help doctors better tailor effective preventative measures such as exercise.

She added: ‘For now, physical activity is the greatest protection, but further research may enable us to prevent and treat insulin resistance, and subsequent diabetes, more effectively.’

The research was published in the journal Experimental Physiology.

[“Source-ndtv”]

 

Xiaomi Mi Note 2 to be priced around $590, new rumor suggests

In a world with no Galaxy Note7 a Note 2 might be exactly what we need. Yes, it’s the XiaomiMi Note 2 we’re talking about, due to be unveiled in just 3 days.

There’s been an abundance of leaks detailing its specs, and also some discrepancies between various sources about its price. Well, now we have a third number, and we’re not sure how to feel about it.

On the one hand, CNY 4,000 ($590) is not a bad price for a dual-curved 5.7-inch Snapdragon 821-packing flagship smartphone, not to mention it’s way less than the originally rumored CNY 5,700 ($845). Then again, the latest info we had stated prices starting at CNY 2,800 ($415) for the base 4GB/64GB version.

source”cnbc”

Leak suggests Meizu M1E will let you control your car remotely

Meizu’s upcoming M1E smartphone – which will likely carry the Blue Charm E moniker in the company’s home country of China – will allow users to control their car remotely, according to a new leak.

The leak suggests that M1E users will be able to unlock their car doors, control air-conditioning, as well as heat up seats using the phone.

There’s, however, a catch: the handset’s car controlling features will only work with the Roewe RX5, which was launched by Chinese e-commerce giant Alibaba and SAIC Motor earlier this year. The former, in case you aren’t aware, has a stake in Meizu as well.

The M1E is set to be made official on August 10.

[“source-gsmarena”]

Slide suggests iPhone 7 can have wi-fi charging and waterproofing

Slide shows iPhone 7 will have wireless charging and waterproofing

Rumors approximately the iPhone are like fishermen’s stories – they develop bolder and grander as timegoes on. A photo of a presentation slide lists the highlights of the imminent phone.

The slide indicates an iPhone 7 Pro (dual cameras) however is labeled iPhone 7 Plus. That aside, thecellphone will run iOS 10 (obviously) and could lack a headphone jack ( a rumor that has been confirmedand denied numerous times through unofficial sources).

It will allegedly have wi-fi charging and might be water-proof. The ones are two matters that Apple hasn’t touched, even as they may be becoming more and more not unusual on Android telephones.

This isn’t always the first time we have heard of a water-resistant iPhone 7 with wi-fi charging, but we’re stillnot prepared to consider it. Subsequent element you know, people will start speakme about a microSD slot.

Zika virus at once infects brain cells and evades immune system detection, look at suggests

Zika may be unfold via inflamed mosquitos or thru sexual sex. In adults, the signs are typically moderateand encompass fever, rash, joint pain, and red eyes. but, Zika virus can motive a critical start defectreferred to as microcephaly, and different excessive neurological consequences such as eye problems,hearing loss, and impaired growth in toddlers born to girls who shrunk the virus while pregnant.
credit: © vchalup / Fotolia
The mosquito-borne Zika virus related to microcephaly and different neurological issues in newborns of affected mothers without delay infects the brain progenitor cells destined to become neurons, UT Southwestern medical center researchers report in a take a look at published on line in cell reports.

The group of researchers used a pressure of Zika currently impacting the Americas, and found that the virus infects approximately 20 percentage of cells on average, evades immune device detection, and keepsto copy for weeks.

“The cell machine we studied mirrors what pathologists are locating in the mind tissue of affected toddlersand could be valuable for similarly expertise how Zika causes excessive mindrelated troubles. Thegadget may additionally serve as a platform for testing new therapies focused on the virus,” said Dr. John Schoggins, Assistant Professor of Microbiology at UT Southwestern and senior author of the observe.

Zika may be unfold through infected mosquitos or via sexual intercourse. In adults, the signs aregenerally slight and encompass fever, rash, joint ache, and crimson eyes. but, Zika virus can purpose aserious delivery disorder referred to as microcephaly, and other severe neurological results which include eye problems, hearing loss, and impaired increase in toddlers born to ladies who contracted the virus when pregnant, according to the centers for ailment control and Prevention (CDC).

The CDC’s internet site lists a chain of unanswered questions about the virus that the sector fitnessorganisation (WHO) has declared a public health emergency of worldwide situation. The unanswered questions consist of whilst for the duration of pregnancy the infection may also harm the fetus and the way the virus affects individual pregnancies.

there was an offer that the detrimental outcomes of the virus is probably linked to its ability to infectmind cells, mainly the progenitor cells that supply upward thrust to neurons,” said Dr. Schoggins, a Nancy Cain and Jeffrey A. Marcus scholar in scientific studies, in Honor of Dr. invoice S. Vowell.

“We confirmed that neural progenitors can be infected via a stress of Zika virus that is currently infectinghumans within the Americas,” Dr. Schoggins stated. “We found that the virus kills some neural progenitor cells, however not all. other cells survive the contamination, and relatively, preserve to duplicate the virus for plenty weeks. in addition, it appears that Zika virus does no longer stimulate a great deal of an immune reaction.”

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Low-salt diets may not be beneficial for all, study suggests

A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption.

In fact, the study suggests that the only people who need to worry about reducing sodium in their diet are those with hypertension (high blood pressure) and have high salt consumption.

The study, involving more than 130,000 people from 49 countries, was led by investigators of the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences.

They looked specifically at whether the relationship between sodium (salt) intake and death, heart disease and stroke differs in people with high blood pressure compared to those with normal blood pressure.

The researchers showed that regardless of whether people have high blood pressure, low-sodium intake is associated with more heart attacks, strokes, and deaths compared to average intake.

“These are extremely important findings for those who are suffering from high blood pressure,” said Andrew Mente, lead author of the study, a principal investigator of PHRI and an associate professor of clinical epidemiology and biostatistics at McMaster’s Michael G. DeGroote School of Medicine.

“While our data highlights the importance of reducing high salt intake in people with hypertension, it does not support reducing salt intake to low levels.

“Our findings are important because they show that lowering sodium is best targeted at those with hypertension who also consume high sodium diets.”

Current intake of sodium in Canada is typically between 3.5 and 4 grams per day and some guidelines have recommended that the entire population lower sodium intake to below 2.3 grams per day, a level that fewer than five per cent of Canadians and people around the world consume.

Previous studies have shown that low-sodium, compared to average sodium intake, is related to increased cardiovascular risk and mortality, even though low sodium intake is associated with lower blood pressure.

This new study shows that the risks associated with low-sodium intake — less than three grams per day — are consistent regardless of a patient’s hypertension status.

Further, the findings show that while there is a limit below which sodium intake may be unsafe, the harm associated with high sodium consumption appears to be confined to only those with hypertension.

Only about 10 per cent of the population in the global study had both hypertension and high sodium consumption (greater than 6 grams per day).

Mente said that this suggests that the majority of individuals in Canada and most countries are consuming the right amount of salt.

He added that targeted salt reduction in those who are most susceptible because of hypertension and high salt consumption may be preferable to a population-wide approach to reducing sodium intake in most countries except those where the average sodium intake is very high, such as parts of central Asia or China.

He added that what is now generally recommended as a healthy daily ceiling for sodium consumption appears to be set too low, regardless of a person’s blood pressure level.

“Low sodium intake reduces blood pressure modestly, compared to average intake, but low sodium intake also has other effects, including adverse elevations of certain hormones which may outweigh any benefits. The key question is not whether blood pressure is lower with very low salt intake, instead it is whether it improves health,” Mente said

Dr. Martin O’Donnell, a co-author on the study and an associate clinical professor at McMaster University and National University of Ireland Galway, said: “This study adds to our understanding of the relationship between salt intake and health, and questions the appropriateness of current guidelines that recommend low sodium intake in the entire population.”

“An approach that recommends salt in moderation, particularly focused on those with hypertension, appears more in-line with current evidence.” The study was funded from more than 50 sources, including the PHRI, the Heart and Stroke Foundation of Canada and the Canadian Institutes of Health Research.

too much folate in pregnant women increases danger for autism, examine suggests

ladies who plan on turning into pregnant are informed they need sufficient of the nutrient folate to make sureright neurodevelopment in their babies, however new research from the Johns Hopkins Bloomberg faculty of Public fitness suggests there can be critical risks in having far an excessive amount of of the equalnutrient.

The researchers determined that if a brand new mom has a totally high stage of folate proper after givingbirthmore than four times what’s taken into consideration adequate — the threat that her toddler willexpand an autism spectrum sickness doubles. Very excessive vitamin B12 stages in new moms are alsopotentially harmful, tripling the hazard that her offspring will increase an autism spectrum ailment. If eachranges are extraordinarily high, the threat that a infant develops the disorder will increase 17.6 instances. Folate, a B vitamin, is determined certainly in fruits and vegetables, at the same time as the syntheticversion, folic acid, is used to support cereals and breads in the united states and in diet dietary supplements.

The findings can be presented may additionally 13 at the 2016 worldwide meeting for Autism studies in Baltimore.

adequate supplementation is shielding: that’s nonetheless the story with folic acid,” says one of the have a look at‘s senior authors M. Daniele Fallin, PhD, director of the Bloomberg college‘s Wendy Klag middle for Autism and Developmental Disabilities. “we’ve lengthy regarded that a folate deficiency in pregnant moms isunfavourable to her infant‘s improvement. however what this tells us is that immoderate quantities may additionally purpose damage. We ought to goal for greatest stages of this crucial nutrient.”

Folate is important in cellular growth and promotes neurodevelopmental increase. Deficiencies early inpregnancy were connected to beginning defects and to an elevated danger of growing an autism spectrumsickness. And no matter this push to ensure women get good enough folate, a few ladies still don’t getenough or their bodies are not properly absorbing it, main to deficiencies. The facilities for sickness manageand Prevention says that one in four ladies of reproductive age within the U.S. have insufficient folate levels.tiers aren’t robotically monitored in the course of being pregnant.

Autism spectrum ailment is a neurodevelopmental condition characterized by way of social impairment,bizarre conversation and repetitive or unusual conduct. One in sixty eight kids in the U.S. have thesickness, with boys five instances much more likely than women to have it. The reasons remain unclearhowever studies shows the factors are a combination of genes and the environment.

For the take a look at, researchers analyzed records from 1,391 momchild pairs inside the Bostonbeginning Cohort, a predominantly low-income minority populace.

The mothers were recruited on the time in their child‘s start between 1998 and 2013 and accompanied fornumerous years, with the mother‘s blood folate levels checked as soon as inside the first one to three days of shipping. The researchers determined that one in 10 of the women had what is taken into considerationan extra amount of folate (more than fifty nine nanomoles per liter) and six percent had an extra amount ofvitamin B12 (more than six hundred picomoles consistent with liter).

the sector health employer says that between 13.5 and 45.3 nanomoles consistent with liter is an good enough quantity of folate for a woman in her first trimester of pregnancy. in contrast to with folate, there are not wellestablished thresholds for adequate vitamin B12 tiers.

A big majority of the mothers in the observe stated having taken multivitamins — which might encompass folic acid and nutrition B12 — at some point of pregnancy. however the researchers say they do not knowprecisely why a number of the girls had such excessive tiers of their blood. it could be that they ate up too many folic acid-fortified ingredients or took too many supplements. Or, they say, it can be that a few ladiesare genetically predisposed to absorbing more portions of folate or metabolizing it slower, main to the excess. Or it is able to be a mixture of the two.

more research is wanted, the scientists say, so one can decide just how a whole lot folic acid a girl must eatin the course of being pregnant to have the first-rate hazard that she can have optimum blood folate stagesto ensure her offspring’s fitness.

With many styles of nutrition dietary supplements, the traditional know-how has been that too much isn’t always dangerous, that the body will flush out the extra. That might not be the case with folic acid and dietB12.

“This research indicates that this can be the case of an excessive amount of of a very good aspect,” sayshave a look at lead writer Ramkripa Raghavan, MPH, MSc, a DrPH candidate within the branch ofpopulation, family and Reproductive health at the Bloomberg college. “We inform girls to make sure to get folate early in being pregnant. What we need to parent out now could be whether there ought to be extra tipsabout simply what an premier dose is for the duration of pregnancy.”