New Study Shows This Common OTC Pain Reliever Has a Really Scary Side Effect

Ibuprofen, a common over-the-counter pain reliever, has a troubling side-effect that’s often overlooked, but new findings have proved it’s more important to know about this now than ever before. Recent evidence found that non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, can increase your chances of having a heart attack in as little as one week of continuous use.

In a recent study published in the British Medical Journal, data from almost 450,000 people, 61,460 of whom had suffered a heart attack, was analyzed looking for the effect over time of taking three common anti-inflammatory painkillers: ibuprofen, diclofenac and naproxen. The data revealed that compared with people who didn’t take the painkillers, those who did ingest them had a 20 percent to 50 percent increased risk of having a heart attack.

Additionally, the risk was found to be higher for people who ingested 1,200 mg a day of ibuprofen (about six tablets of Advil) and 750 mg a day for naproxen (about three and a half Aleves), Yahoo! reports. The study reported that it only took a week for a higher risk of heart attack to set in on a person, with the highest risk occurring at about a month of usage. After a month, researchers found that the risk didn’t increase further but rather stayed the same.

Typically, NSAIDs are safe when used correctly for mild pain relief, however, many people have begun relying on NSAIDs for prolonged periods of time at a higher dosage to treat their pain, which is why the risk of heart attack associated with the use of NSAIDs has begun to rise.

While this study certainly revealed a scary truth about the drug, it’s important to note that taking an NSAID for minor pain relief at the lowest effective dose and a minimal length of time isn’t likely to cause aheart attack. It’s the usage level over a longer time period at higher dosage that can be dangerous, so it’s best to limit your use as much as possible to avoid any unwanted negative side effects.

 

 

 

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MS vision loss might be helped by way of OTC drug

Glasses with blurred vision

antihistamine this is bought over-the-counter to treat allergies has been shown to partially reverse visionharm in people with a couple of sclerosis. effects of the examine are being offered this week at the yankeeAcademy of Neurology’s 68th Annual meeting in Vancouver, Canada.
Glasses with blurred imaginative and prescient
Blurred imaginative and prescient is often one of the first symptoms of MS, typically acting between 20-40years of age.
The drug, known as clemastine fumarate, is a histamine H1 antagonist, because of this it blocks histaminemotion at the H1 receptor, relieving allergic symptoms.

imaginative and prescient harm is a trademark of a couple of sclerosis (MS), a disease of the vital fearfuldevice. It entails disrupted communique between the brain and different elements of the frame.

MS is typically seemed as an autoimmune disease, wherein the body launches an assault on its very ownmyelin, that’s the protecting coating around the nerves.

First signs of MS generally appear between 20-40 years of age. the same old first symptoms are blurred or double imaginative and prescient, crimsoninexperienced coloration distortion or blindness in one eye.

additionally, the majority with MS come across muscle weakness and issue with coordination and balance, which may be excessive enough to prevent on foot or standing.

due to the fact the immune system destroys myelin, it finally damages the nerves themselves. indicators to and from the mind emerge as tons slower. As a end result, optic nerve damage is common in MS.

‘First time a drug has in all likelihood reversed damage accomplished with the aid of MS’
for his or her have a look at – led by Dr. Ari inexperienced, of the multiple Sclerosis center at the universityof California-San Francisco (america) – the researchers used 50 individuals with MS and optic neuropathy,that’s harm to the nerve that sends indicators from the eye to the mind.

fast statistics about MS
MS is a disorder of the crucial nervous machine
initial signs typically gift themselves among 20-forty years of age
there may be currently no cure.
learn extra about MS
Over the course of 5 months, the participants – who have been of a median age of 40 and who had MS for a median of 5 years – carried out vision tests at the start and quit of the examine.

The researchers note that each one participants had evidence of a stable continual optic neuropathy, this means that they have been no longer getting better from their vision harm.

For one visible take a look at, the researchers recorded the time it took for a signal to tour from the retina to the visual cortex. For a player to be included, they needed to have a transmission delay longer than 118 milliseconds in as a minimum one eye, as well as evidence that they’d a sufficient quantity of nerve fibers to reinsulate.

according to the group, improvement in transmission delay is a biomarker of myelin restore.

all through the first three months of the take a look at, contributors have been either given clemastine fumarate or a placebo. Then, for the second 2 months, the contributors to begin with given the placebo had been given the drug, and vice versa.

outcomes confirmed that the patients who were taking the drug exhibited decreased delays in every eye –an average of approximately 2 milliseconds.

“This have a look at is exciting because it is the primary to demonstrate viable repair of that shieldingcoating in people with continual demyelination from MS,” says Dr. green. He provides that it “becameaccomplished the use of a drug that was identified at usa only 2.5 years in the past as an agent with theability to help mind repair.”

however, he warns that more research needs to be conducted earlier than doctors can suggest the drug forhuman beings with MS.

Dr. green adds:

Finish

MS vision loss can be helped by OTC drug

m
1
An antihistamine that is sold over-the-counter to deal with allergic reactions has been shown to partiallyopposite imaginative and prescient damage in people with multiple sclerosis. results of the take a look at are being offered this week at the american Academy of Neurology’s 68th Annual assembly in Vancouver, Canada.
Glasses with blurred vision
Blurred vision is often one of the first signs and symptoms of MS, normally performing among 20-40years of age.
The drug, known as clemastine fumarate, is a histamine H1 antagonist, because of this it blocks histaminemotion at the H1 receptor, relieving allergic signs and symptoms.vision damage is a hallmark of more than one sclerosis (MS), a disease of the imperative apprehensivemachine. It entails disrupted verbal exchange among the brain and other components of the body.

MS is by and large seemed as an autoimmune sickness, whereby the body launches an assault on itspersonal myelin, that’s the protective coating around the nerves.

First signs and symptoms of MS typically seem among 20-40 years of age. the same old first signs and symptoms are blurred or double vision, pinkgreen shade distortion or blindness in a single eye.

additionally, most of the people with MS come across muscle weak spot and trouble with coordination and stability, which may be severe sufficient to avoid taking walks or status.

because the immune system destroys myelin, it sooner or later damages the nerves themselves. signals to and from the mind turn out to be tons slower. As a result, optic nerve damage is not unusual in MS.

‘First time a drug has in all likelihood reversed damage done by way of MS’
for their have a look at – led by using Dr. Ari green, of the more than one Sclerosis middle at theuniversity of California-San Francisco (u.s.a.) – the researchers used 50 members with MS and optic neuropathy, which is damage to the nerve that sends indicators from the attention to the mind.

rapid statistics approximately MS
MS is a ailment of the vital anxious system
preliminary signs and symptoms typically gift themselves between 20-forty years of age
there is presently no treatment.
learn greater about MS
Over the course of five months, the members – who have been of an average age of forty and who had MS for an average of five years – done imaginative and prescient exams at the start and give up of the take a look at.

The researchers note that every one contributors had evidence of a solid continual optic neuropathy,because of this they have been no longer improving from their imaginative and prescient damage.

For one visible take a look at, the researchers recorded the time it took for a signal to journey from the retina to the visual cortex. For a player to be protected, they had to have a transmission delay longer than 118 milliseconds in at the least one eye, in addition to proof that they’d a enough amount of nerve fibers to reinsulate.

in line with the crew, development in transmission delay is a biomarker of myelin restore.

at some point of the primary 3 months of the observe, participants were both given clemastine fumarate or a placebo. Then, for the second one 2 months, the contributors initially given the placebo had beengiven the drug, and vice versa.

effects confirmed that the patients who were taking the drug exhibited decreased delays in each eye – a mean of about 2 milliseconds.

“This look at is exciting due to the fact it’s miles the first to illustrate possible restore of that protectivecoating in humans with persistent demyelination from MS,” says Dr. inexperienced. He provides that it “become completed using a drug that changed into identified at america only 2.5 years in the past as an agent with the potential to help brain repair.”

but, he warns that more studies wishes to be conducted before medical doctors can advise the drug forhumans with MS.

Dr. inexperienced adds:

Finish