Ibuprofen, a common over-the-counter pain reliever, has a troubling side-effect that’s often overlooked, but new findings have proved it’s more important to know about this now than ever before. Recent evidence found that non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, can increase your chances of having a heart attack in as little as one week of continuous use.
In a recent study published in the British Medical Journal, data from almost 450,000 people, 61,460 of whom had suffered a heart attack, was analyzed looking for the effect over time of taking three common anti-inflammatory painkillers: ibuprofen, diclofenac and naproxen. The data revealed that compared with people who didn’t take the painkillers, those who did ingest them had a 20 percent to 50 percent increased risk of having a heart attack.
Additionally, the risk was found to be higher for people who ingested 1,200 mg a day of ibuprofen (about six tablets of Advil) and 750 mg a day for naproxen (about three and a half Aleves), Yahoo! reports. The study reported that it only took a week for a higher risk of heart attack to set in on a person, with the highest risk occurring at about a month of usage. After a month, researchers found that the risk didn’t increase further but rather stayed the same.
Typically, NSAIDs are safe when used correctly for mild pain relief, however, many people have begun relying on NSAIDs for prolonged periods of time at a higher dosage to treat their pain, which is why the risk of heart attack associated with the use of NSAIDs has begun to rise.
While this study certainly revealed a scary truth about the drug, it’s important to note that taking an NSAID for minor pain relief at the lowest effective dose and a minimal length of time isn’t likely to cause aheart attack. It’s the usage level over a longer time period at higher dosage that can be dangerous, so it’s best to limit your use as much as possible to avoid any unwanted negative side effects.
Here we are, almost a week after Ubisoft sprayed farts into my nose, and I’m still feeling a bit sick. Was it actually farts? Or was it something worse? Maybe tuberculosis, or black plague, or anthrax. Or maybe they ground up the source code for Watch Dogs and shot it straight into my nose. That would certainly explain the feelings of impending illness.
Anyway, some news happened this week. Mass Effect Andromeda showed off some new game footage, Interplay put itself up for auction, Deus Ex added DX12, and Shadow Warrior 2 killed a lot of people. Like, a lot. This is gaming news for September 5 through 9.
Free games are always good, right? Even if it’s Ubisoft’s middling open-world racer The Crew? The latest in Ubi’s 30th anniversary celebration, The Crew will be free through Uplay starting September 14—meaning for the next four days, you can still grab a copy ofRayman Origins if you haven’t already.
And Humble is giving away copies of city-builder Tropico 4 until mid-day Saturday, redeemable on Steam. Might as well grab it.
Er…also Steam will let you play Homefront: The Revolution for free this weekend. It’s in your game library. Personally I’d recommend you do literally anything else with your Saturday and Sunday.
Interplay, one of the foremost publishers of the ‘80s and ‘90s, announced this week that it will sell off the rest of its remaining assets to those who want a piece. It’s a sad end to a storied company—one that developed The Bard’s Tale, Wasteland, and Fallout and published Baldur’s Gate, Carmageddon, Planescape: Torment , Descent, Earthworm Jim,Freespace 2, and about a hundred other games.
Not that Interplay in 2016 is the same as Interplay in 1999—that mantle’s been passed to Obsidian and inXile. But still, it’s one hell of a loss.
Come on, Mass Effect
You’re excited for Mass Effect Andromeda? I’m excited for Mass Effect Andromeda. I think most people are excited about Mass Effect Andromeda (where people is: the subset that plays big-budget games).
That being said: Come on, EA. This has to be one of the most generic, boring trailers you could put together for a series as storied as Mass Effect. Someone give me the over-under on this game being delayed again come 2017.
No matter how prolific Telltale gets, no matter how many new games it churns out, I still have a soft spot for The Walking Dead—the first of the modern Telltale era. News this week has the third season of The Walking Dead, subtitled A New Frontier, hitting in November. Go ahead, do a little fist pump. And then check out this key art:
There’s yet another adventure game hitting in November. Daedalic announced this week that Silence, its follow-up to The Whispered World, will arrive on November 15. I’m excited for this one, both because I like the universe and because Daedalic’s grown a lot as a studio in the years since—The Whispered World feels incredibly dated, post-Memoria.
And in case you missed the Gamescom trailer:
A better aug
Still playing Deus Ex: Mankind Divided? Haven’t started it yet? Well lucky you, because Eidos Montreal pushed DirectX 12 support to the game this week. Sort of.
If you right-click on the game in Steam, go down to Properties, and click the Beta tab you should be able to opt in to the new “dx12_preview” branch. This is an unofficial preview for DX12 support, so as Eidos says, expect “minor hiccups.” Radeon cards tend to see decent performance increases, while GeForce cards are experiencing massive performances drops in this beta DX12 release. Stick to DX11 if you’re packing Team Green’s goods.
League of Geeks, the developer behind digital board game Armello, announced last week that it would be bringing out new DLC for the game—but only to the Steam version. And GOG.com owners of the DRM-free version? Left out in the cold with no (concrete) explanation given.
Lucky for you, GOG.com seems to be made up of some kind-hearted individuals. If you’re one of the unlucky ones who now owns a lesser version of Armello, GOG is offering refunds, no questions asked.
Prey for me
After keeping dark on Prey for years and years and years, Bethesda sure is ripping the lid off this game with all the force of a nuclear bomb. Trailer at E3. Trailer at QuakeCon. And now, yet more Prey footage:
(Via PC Gamer)
Off with their heads
This new trailer for Shadow Warrior 2 opens with decapitated bodies and gets more gruesome from there. Consider yourself warned.
We’re keeping it brief this week because, nicely, Doom is fantasticand iwantto goback to playing.
This week in video games: The assassin’s Creed filmgets a trailer, Diablo receives a postmortem, and Lionhead employees recount the time Peter Molyneux told his group “The hero has a dog and it dies” after which disappeared for 2 weeks at some point ofmyth II improvement.
advertising and marketing
That crazy Peter Molyneux.
Suns out, weapons out each ends of the first–character shooter spectrum are unfastened on Steam this weekend. in case you’re a run ‘n’ gun kind, call of obligation: Black Ops III’s multiplayer is unfastened from now until 1 p.m. on Monday.
howeveradditionallyloose for the weekend is call of obligation’s antithesis, the “move slowly40minswithin themudsimply to die” thrill journeythis is Arma 3. It’s freetill 1 p.m. Sunday. selections,alternatives.
(Or you couldsimplypurchase and play Doom.)
fight them on thebeaches
Stellaris, Paradox’s space-faring grand strategyrecreation, justreleasedin advance this week. And it’sprettygood.
but lest ye forget about, there’s every other Paradox grand strategysport mere weeks away—Hearts of Iron IV is due tolaunch on June 6, D-Day. Take a glance:
behind the curtain at EA
We’re neverthelesssome weeks out from E3/EA Play but that didn’t forestall the writer from pronouncinga bevy of launch dates this week. The terriblenews? most of them are in 2017.
The these days–announced Battlefield 1 will proportionthe autumn with Titanfall 2 this year, soindividuals who don’t want to play globalstruggle I trenchfoot simulator can bounce into mechs and runacrosswalls and something.
however Mass effect Andromeda has slipped its release date and is now because of arrive in Q1 2017. Andadditionallybecause of arrive in 2017: some otherwant for pacesport and a 2dbig name Wars Battlefront. with a bit of luckeachmight bebetter than their predecessors.
Breaking down Diablo
You is probablyusuallyfamiliar with the game Developer’s convention (GDC) as itway a rash ofinformation and previews in March, but thebestpart is truelyapproximatelygames from our past. eachyear, GDC holds a number of “classicsport Postmortems,” wheredevelopers come talkapproximatelythe procedureof makingsome of your favouritevideo games.
Momentum is growing, in particularamong millennials, to place your moneyin which your values are. Spotlighting this trend is the latest Chan Zuckerberg Initiative, through which 31-yr–vintagefacebookfounder Mark Zuckerberg and his wife Priscilla Chan, also 31, have pledged $45 billion to enhancethe world.
This altruistic hobby is being meditatedin therapid–developing socially accountablemaking an investment universe, which has advanced from mostlynice or poor screening of investments toadditionallyencompass so-calledimpact investments.
inexperiencedelectricitymaking an investment
tzahiV | Getty photographs whilstthere are numerous interpretations of the termimpactmaking an investment, it could be summed up as investing for measurable and nice environmental, social or governmental (ESG) results with afinancialgo back. The massive and new concept is that traderswantnotgive upmarket returns whilstinvesting for the moreright.
lengthyto be had to establishments, impactmaking an investmentmotors are simplybeginning toemerge for the non-accredited investor. Examples of theseencompass:
Public equity mutual budgetoffering shareholder engagement in the direction ofchangingcompanybehavior.
Bonds and personalfairnessdealsassistingprojects that deal with ESG troubles. communitydevelopmentmortgagefinances. global microfinance loans.
Shane Yonston, licensedmonetary planner and principaladvisor with impactinvestors, founded hispractice with a devotedfocusin thistype ofmaking an investment. He makes use of SRI budget inpatron portfolios as thecenter holdings and dietary supplements them with 10 percentto twentypercentage in impact investments.
The Dow’s ruin above 18,000 this week shouldproperlypoint the manner to in additiongains.
opinions on Wall streetabsolutelyseem like divided at thesignificance of indices growing above round-numbered tiers, such as the 18,000 that the Dow Jones commercialcommon rose above on Monday. somesay that “mentalimportance” is tied to theselevels. The notion is that human beingsmay be led to buystocks or to develop marginally greater bullish as this sort ofstage is handed.
Others say that a range of like 18,000 is nogreatermeaningful than, say, 17,962 — with the onlycapacitydistinction being that the previous is extrawithout problems ballyhooed by the media than the latter.
A look atrecentmarketplacehistory, but, mightgenerally tend to helpthe previous view.
An analysis of the realimportance of spherical numbers startedby means ofisolating the sessionsin which the Dow traded above a brand new thousand-deal withdegreeat thehigh of the day. Then, theoverall performance over the subsequent 10 sessionswasas compared with the overall performance of the Dow over a median 10-sessionlength.
It seems that over the last5 years, the Dow rose a median of 0.7 percentageinside the 10 periodsfollowing the touching of a brand new -000 level. This compares with the commonupward push of zero.32percentageacross all 10-day durations. The difference in median performances is just as stark, with aupward pushof 1.01 percentageseen after the touching of a newround-numbered degree, comparedwith zero.fifty onepercentageacross all 10-sessionperiods.
advancedoverall performance following the tapping of round numbers alsohas a tendency to be seenwhen 30-day performance is analyzed, as well aswhilst longer or shorter time frames are taken into consideration.
common Dow overall performance over…
All 10-day durationszero.24% zero.32% –zero.01%
10-day periods after higher -000 degree hit 0.32% zero.70% 1.03%
All 30-day intervals0.sixty nine% 0.96% –0.09%
30-day durations after better -000 level hit zero.sixty six% 1.eighty% 0.82%
The overall performanceisn’t alwaystrulybecause of an regular momentum impactwhereinsharestended to upward push after up days, nor due to the factdurations following the touching of roundnumbers had beengreaterrisky in general (they’venot been).
There appears to be, as an alternative, some thingapproximately the seize or recapture of a roundvariety that draws in marginal consumers, and perhaps even grabs the creativeness.