Forget lifestyle – we need to end poverty to combat cancer

The Minister for Health, Simon Harris, and Minister of State for Health Promotion, Catherine Byrne, during the launch of a new ‘National Cancer Strategy 2017-2026’ at Iveagh House, Dublin. Photograph: Gareth Chaney Collins

From the point of view of early diagnosis, treatment, and support for survivors, the new National Cancer Strategy 2017-2026 is an excellent document. However, the prevention section is a big disappointment. According to the foreword by the Minister for Health, Simon Harris, “cancer prevention is a cornerstone of this strategy as it offers the most cost-effective, long-term approach for cancer control”.

Prof John Kennedy, chairman of the steering group that put the strategy together, also stresses the need for prevention and aggressive programmes of public education and “that the most strenuous efforts must be made to target more deprived populations in cancer prevention”.

Although recognising the “incontrovertible evidence of the enormous impact of socioeconomic status and deprivation on death rates from some cancers Ireland”, he blames smoking and poor diet. In fact, the prevention chapter is all about the promotion of healthy lifestyles. This approach will not prevent cancer or reduce inequalities.

Did the members disregard the evidence that inequality and health inequality are the main cancer risk factors? No, they knew about the health impact of inequality. “Reducing health inequalities is a priority of this strategy, as lifestyle risk factors generally follow social, deprivation, gender, and age patterns.” The steering group included a representative from the National Cancer Registry which produced a report on cancer inequalities last year titled Cancer Inequalities in Ireland by deprivation, urban/rural status and age: A National Cancer Registry Report 2016.

This report showed that not only was there a higher incidence of cancer in deprived populations but these populations had much lower survival rates. “Strong patterns of inequality . . . are documented for most of the measures examined [nine major cancer types].” None of the proposed prevention actions in the new cancer strategy will reduce inequality and may widen the health gap between socioeconomic groups. It is more likely that the steering group recognised the impact of inequality but did not know what to do about it.

There is overwhelming evidence that focusing on getting the lifestyle message across and public health education does not prevent cancer or any other disease. Prevention groups know that poor people get sick more often than those who are better off but do not analyse the problem. They assume it is a health education issue and believe that if only “the poor” realised that smoking, drinking, and being overweight was bad for their health they would change their behaviour. Because of this erroneous belief, health professionals, the Department of Health and the HSE rely on health information campaigns. They believe that if they say it often enough people will change.

For example, Goal 1 in the National Cancer Strategy is directed at reducing the cancer burden by focusing on health inequalities through information campaigns. “A significant effort is required to ensure that prevention and awareness campaigns have a particular focus on addressing health inequalities” and “it is vital that we are effective in getting the message across to the population that each person can impact significantly on their own level of risk of developing cancer.” This is so stupid.

According to Margaret Whitehead, a World Health Organisation expert on the social determinants of health and health inequalities, “the solutions may seem so complex that people can easily become frozen into inaction” leading to “lifestyle drift.” In 1988, she wrote The Health Divide which analysed the huge differences in health between socioeconomic groups.

According to a 2016 paper by Whitehead, the reason poor people do not adopt healthy lifestyles is because they do not control their own destiny. “Being in a low social position; living in a disadvantaged environment with a sense of collective threat and powerlessness and the degree to which people are discriminated against and excluded from the society in which they live”, means that people are more likely to develop cancer and other chronic diseases.

According to the new cancer strategy, “As more evidence emerges regarding the development of cancer . . . there will be a need to identify the most effective prevention methods.” We already know the most effective method which is to reduce or, as far as possible, eliminate inequalities and thus health inequalities. Unless this happens the numbers of people with cancer will not just double by 2040, as predicted in the National Cancer Strategy, but treble.

[Source:-.irishtimes]

Spinal health is essential to combat back pain

Take care of your spine (Thinkstock)Take care of your spine (Thinkstock)
Experts feel that, when it comes to maintaining spinal health, even small changes can help with the healing process over a period of time. Here are some simple ways to support your spine. Keeping these tips in mind will help you prevent back pain issues.

Rest your spine in the correct way
When lying down, make sure that your mattress and pillows allow your spine to rest and be comfortable by giving it proper support. So choose the best mattress that does not harm your spine.

Strengthen your core
Your back and abdominal muscles need to be strong and supple always. Tone them through specific, targeted exercises. Strong core helps to support your spine and take the pressure off your lower back.

Wear the right shoes

Most do not know this, but your shoes are every important when it comes to your spine health. The right shoes support your lower back and keep your spine and body aligned.

Sitting the right way is essential

You must practise good ergonomics while sitting. Limiting the total amount of sitting time is essential. If your job entails sitting down for long, you must take 15 minute breaks every couple of hours. Your spine has to handle pressure if you are sitting for long and slouching or leaning aggravates back pain.

Choose the right chair

Sitting on a chair that encourages a good posture and supports all the natural curves of your back is essential if you want to deal with back pain for good.

source”cnbc”

New drug can create ‘good’ fat to combat obesity

<p>New drug can create 'good' fat to combat obesity<br></p>New drug can create ‘good’ fat to combat obesity

Scientists have identified a new drug that can create beneficial “brown” or “good” fat to boost metabolism, combat obesityand Type II diabetes.

Researchers from Gladstone Institutes San Francisco in the US treated mice with a drug called bexarotene (Bex) and found they had more “brown fat, faster metabolisms and less body weight gain, even after being fed a high-calorie diet”.

“All current weight loss drugs control appetite and there is nothing on the market that targets energy expenditure. Introducing brown fat is an exciting new approach to treating obesity and associated metabolic diseases, such as diabetes,” said Baoming Nie from the Gladstone Institutes.

Scientists used cellular reprogramming to convert muscle precursor cells and white fat cells into “brown” fat cells and said it could be a new way to combat obesity and type II diabetes.

“Bex acts on a protein called retinoid X receptor (RXR), which controls a network of other cellular proteins. Specifically, when RXR was stimulated by Bex, it turned on genes needed to produce “brown” fat and turned off genes linked to white fat or muscle,” the study explained.

Brown fat, unlike white fat, helps the body burn energy through heat.

“However, while Bex is very effective at creating brown fat cells, it is not a very specific drug, and there are several potential side effects that may arise from taking it,” said Sheng Ding from Gladstone.

Researchers noted that infants are born with small amounts of brown fat, but as they age, most of it disappears.

“In adults, people with higher amounts of brown fat have lower body mass, and increasing brown fat by as little as 50 grams could lead up to a 10 to 20 pound weight loss in one year,” noted the study published in the journal Cell Reports

source”cnbc”

Cough virus helps combat liver cancer in adulthood

Cough virus helps combat liver cancer in adulthoodCough virus helps combat liver cancer in adulthood
A virus that cause respiratory illnesses and stomach upsets in children could help in the fight against primary liver cancer, according to a study. Reovirus stimulates the body’s own immune system to kill off the cancerous cells and is also able to kill off the hepatitis C virus – a common cause of primary liver cancer – at the same time, the researchers at the University of Leeds discovered.

These early stage findings are important because primary liver cancer is the third highest cause of cancer deaths worldwide and, if surgery is not an option, the prognosis is poor. Study co-leader Dr Stephen Griffin, Associate Professor of Viral Oncology at the University of Leeds, said: “Ultimately we hope that by simultaneously treating the tumor, and the hepatitis virus that is driving the growth of the tumor, we may provide a more effective therapy and improve the outcomes for patients.

“Current treatments for liver cancer that can’t be removed by surgery are mainly palliative with chemotherapy only tending to prolong life, rather than cure and it can have significant side effects.” The University of Leeds team found that Reovirus was successful in treating both liver cancer cells grown in the laboratory and those taken directly from patients undergoing surgery.

When introduced into the body, Reovirus stimulates an immune system factor known as interferon, which in turn causes the activation of a specific white blood cell called a Natural Killer cell. These Natural Killer cells then kill both the tumor, and cells infected with the hepatitis C virus.

Stimulating the immune system to kill cancer cells is known as immunotherapy. It differs from chemotherapy, in which the actual drugs kill the cancer cells. The researchers are now hoping to start the first in-human clinical trials. Study co-leader Professor Alan Melcher, now Professor of Translational Immunotherapy at the Institute of Cancer Research, London, said:

“Our study establishes a completely new type of viral immunotherapy for the most common primary liver cancer type, hepatocellular carcinoma, which has a very poor prognosis in its advanced form.

“Using a mixture of experiments in human cancer samples and mice, our research showed that the Reovirus therapy switches on the host immune system to attack cancer cells – as well as suppressing the replication of hepatitis C virus, which is linked to many hepatocellular cancers.

“We also showed that Reovirus therapy could be used to treat a range of other cancer types associated with viral infection, including Epstein Barr Virus-associated lymphoma.”

Primary liver cancer is cancer that starts in the liver. It is a separate condition from secondary liver cancer, where the cancer originally developed in another part of the body and then spread to the liver.

Most cases of primary liver cancer are associated with damage and scarring of the liver, most commonly from having a hepatitis B or hepatitis C viral infection. Less commonly it is caused by drinking excessive amounts of alcohol over many years.

At least 130 million people globally have chronic hepatitis C infection, according to the World Health Organisation, and a significant proportion of these will develop liver cancer. Co-researcher Dr Adel Samson from the University of Leeds said: “It is becoming increasingly clear that one of the most powerful weapons available to treat cancer is our own immune system.

“However, as cancers are formed from our own cells, the immune system frequently struggles to identify the subtle differences that differentiate cancerous cells from normal cells, without help. “Immunotherapy involves various strategies – such as a virus, as in our study – to kick-start our immune system to better identify and fight cancer.

“These ‘oncolytic’ viruses show great promise in clinical trials, and the first such virus has recently been licensed as a medicine for the treatment of skin cancer.” Dr Justine Alford, senior science information officer at Cancer Research, said: “This study in cells and mice suggests the possibility of using a harmless oncolytic virus as an immune-boosting one-two punch against liver cancer and the cancer-causing hepatitis C virus.

“These early results also suggest this oncolytic virus could be used more widely in the treatment of virus-driven cancers. “In these cancers, the virus es can represent a major hurdle for treatment, so we urgently need new and effective ways to tackle the root of the problem. “The next step will be to see if this technique will work in patients.”

source”cnbc”

Five to Try: Bohemian Rhapsody goes VR, and Family Guy and Futurama wage card combat

fivetotry sept16 lead

When you think of Queen’s iconic “Bohemian Rhapsody,” what pops to mind?Wayne’s World? Maybe next time your brain will go to vivid virtual reality, as Google just released the mesmerizing Bohemian Rhapsody Experience app for Cardboard VR. It leads our latest batch of new Android app and game recommendations, all of which are focused on fun and entertainment.

Also new this week is Fox’s Animation Throwdown, which blends several popular cartoon universes for a card-battling game, along with teen-focused live-streaming app, Live.ly. Six! and MyNBA2K17 round out this week’s pack, so if you want to shake up your phone’s app selection with some new options, here’s a good place to start.

The Bohemian Rhapsody Experience

fivetotry sept16 bohemian
The Experience gradually transforms and shifts between various scenes and styles. Much like the song itself!

“Bohemian Rhapsody” is one of the most instantly recognizable rock songs in history, and now it’s one of the most memorable VR apps for Cardboard. Queen’s classic is the focus of Google’s new app, which concocts a dazzling dream world around the six-minute track. You’ll see odd cartoon creatures, bits of archival video footage, animated versions of the band members, and even dancers and other elements that react based on how you look around.

As a 360-degree experience with spatial sound, The Bohemian Rhapsody Experience is best experienced in a Cardboard viewer—but even if you don’t have one of the low-end VR shells, you can still watch the whole thing in full-screen on your device. It’s short and sweet, but as a free showcase for Cardboard and a tribute to an amazing song, it’s well worth checking out.

When you think of Queen’s iconic “Bohemian Rhapsody,” what pops to mind?Wayne’s World? Maybe next time your brain will go to vivid virtual reality, as Google just released the mesmerizing Bohemian Rhapsody Experience app for Cardboard VR. It leads our latest batch of new Android app and game recommendations, all of which are focused on fun and entertainment.

Also new this week is Fox’s Animation Throwdown, which blends several popular cartoon universes for a card-battling game, along with teen-focused live-streaming app, Live.ly. Six! and MyNBA2K17 round out this week’s pack, so if you want to shake up your phone’s app selection with some new options, here’s a good place to start.

The Bohemian Rhapsody Experience

fivetotry sept16 bohemian
The Experience gradually transforms and shifts between various scenes and styles. Much like the song itself!

“Bohemian Rhapsody” is one of the most instantly recognizable rock songs in history, and now it’s one of the most memorable VR apps for Cardboard. Queen’s classic is the focus of Google’s new app, which concocts a dazzling dream world around the six-minute track. You’ll see odd cartoon creatures, bits of archival video footage, animated versions of the band members, and even dancers and other elements that react based on how you look around.

As a 360-degree experience with spatial sound, The Bohemian Rhapsody Experience is best experienced in a Cardboard viewer—but even if you don’t have one of the low-end VR shells, you can still watch the whole thing in full-screen on your device. It’s short and sweet, but as a free showcase for Cardboard and a tribute to an amazing song, it’s well worth checking out.

fivetotry sept16 lively
I sure hope the teens like watching my cat being annoyed.

Have you heard of Musical.ly? It’s a make-your-own-music-video lipsyncing app like the recent Funimate, and it’s hugely popular with teens, racking up more than 100 million downloads across platforms. And that same crowd will surely snap up the company’s latest addition, Live.ly, which already topped the charts over on iOS. Anyone already familiar with live-streaming apps like Periscope orMeerkat will feel right at home.

That’s because it’s more or less a teen-centric clone, offering the same kind of interface (with chat and streams of emotes) albeit with a more focused target audience. When I checked it out, the top streams included a girl broadcasting from her desk at school, and some kid’s dog chewing a water bottle—about as riveting as the average fare from other live-streaming apps, really. But the ties into the Musical.ly community may give this an edge with the younger crowd.

MyNBA2K17

fivetotry sept16 mynba2k17
Yes, those are basketball cards playing basketball.

NBA 2K17 tips off on consoles today, and 2K Sports’ annual basketball sim just seems to get better every year. We’ll probably get an Android version of the full game at some point, as we did with NBA 2K16 ($8)—but for now, hoops fans can check out MyNBA2K17. Like last year’s game, it’s an odd little amalgamation of basketball and a collectible card game (like Animation Throwdown above), as 2K has also done with WWE SuperCard and NHL SuperCard.

You’ll bring a small deck onto the court in the brief battles, picking your best card for each matchup and trying to beat the opposing team. All the while, the cards dribble and shoot the ball, which is as surreal as it is totally hilarious.MyNBA2K17 also serves as a companion app for the main game, letting you earn in-game currency and scan your face to create custom athletes in the PlayStation 4 and Xbox One versions.

source”cnbc”

Twitter will soon let you use keyword filters to combat online harassment

twitter ios app

Online harassment on Twitter has gotten so bad that some users opt to never read their mentions, while others are driven to log off the platform forever.

Now, Twitter is addressing the problem with a new anti-harassment tool, according toBloomberg. Twitter is developing a feature that would allow users to filter out certain keywords from their timeline and mentions. This anti-harassment feature, which has been in the works for about a year, will give users the power to block certain offensive words and slurs.

This new tool is Twitter’s latest attempt to curb online harassment on its platform. Previously, Twitter made it easier for people to report a string of offensive Tweets, but this feature is the most control the company has ever given its users in the fight against harassment. In addition, the tool could expand to become a general moderation tool, according to Bloomberg, giving users the power to block out entire hashtags, not necessarily because they find them offensive.

Earlier this summer, Instagram gave its high-profile users and businesses a similar tool for filtering out certain keywords in their comments. Bloomberg notes, however, that Instagram’s moderation tool hasn’t been all-catching. Trolls have outsmarted it sometimes by misspelling certain slurs.

Why this matters: Online harassment on Twitter seems to be at an all-time high, giving the platform an unflattering reputation as a hub for haters and trolls. BuzzFeed called Twitter a “honeypot for assholes” because of how it prioritized free speech, even when it’s hateful.

Follow

Eldge @Sickayduh

NBC: remove all tweets with our olympics footage

Twitter: of course

Girl: a guy is harassing me

Twitter: we don’t have the tools for that

  • 21,36521,365 Retweets

  • 29,91929,919 likes

And it’s had some real consequences for the company. Journalists and celebrities havequit Twitter after being the targets of online abuse, which is the last thing you’d want when your company is suffering from years of stagnant user growth. Furthermore, Twitter has been criticized for being quick to ban users who posted unauthorized Olympics GIFs, while failing to ban known trolls and offensive accounts.

According to Bloomberg, curbing this type of harassment has become a priority for Twitter CEO Jack Dorsey. Twitter is expected to unveil more initiatives later this year.

source”gsmarena”

What ingredients can help combat the threat of continual infection?


a new study by means of the college of Liverpool’s Institute of ageing and persistent disease has diagnosedmeals stuffs that could help save you persistent irritation that contributes to many leading reasons of death.

inflammation takes place evidently inside the frame but whilst it is going incorrect or goes on too long, it is able to trigger sickness tactics. out of control infection plays a role in lots of most important sicknesses,which includes cancer, heart disorder, diabetes and Alzheimer’s disorder.

Diets rich in culmination and vegetables, which contain polyphenols, shield in opposition to age-relatedinflammation and chronic sicknesses.

cellular-to-cellular conversation

Polyphenols are plentiful micronutrients in our eating regimen, and evidence for their function in theprevention of degenerative diseases inclusive of most cancers and cardiovascular illnesses is alreadyemerging. The health outcomes of polyphenols rely on the amount ate up and on their bioavailability.

T-cells, or T-lymphocytes, are a kind of white blood cell that circulate around our bodies, scanning for cellularabnormalities and infections. They contribute to cellular signalling molecules (cytokines) that resourcemobile-to-mobile communique in immune responses and stimulate the movement of cells towards sites ofirritation, contamination and trauma. Cytokines are modulated with the aid of fruit and vegetable intake.

Little is known approximately the relative potency of various (poly)phenols in modulating cytokine release by means of lymphocytes.

seasoned-inflammatory mediators

The take a look at, carried out by using Sian Richardson and Dr Chris Ford from the university‘s Institute ofgetting old and continual disorder, tested the one-of-a-kind potencies of the polyphenols.

Sian Richardson, said: “The outcomes of our have a look at propose that (poly)phenols derived from onions, turmeric, crimson grapes, inexperienced tea and açai berries may additionally help lessen the release ofpro-inflammatory mediators in humans susceptible to chronic inflammation.

“Older human beings are greater susceptible to continual irritation and as such they will benefit from supplementing their diets with isorhamnetin, resveratrol, curcumin and vanillic acid or with meals resourcesthat yield these bioactive molecules.”